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KMID : 0374019840070010003
Ewha Medical Journal
1984 Volume.7 No. 1 p.3 ~ p.7
The Effects of Vitamin A and E on Lipid Peroxidation in Ethanol Administered Rat Liver Microsomes



Abstract
Ethanol enhances the activity of microsomal enzyme system and lipid peroxidation.. We observed the effect of chronic ethanol administration on cytochrome P- 450 level and lipid peroxidation in rat liver microsome.
lChe results were as follows:
1) When rats were administered with ethanol, the level of microsomal cytochrome P-450 was decreased and lipid peroxidation did not change significantly.
2) When vitamin A and E were added incubation medium in each group, lipid per-¢¥oxidation was decreased significantly.
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